Scientist, Sxy Lab (Imcb) (2719)

Job Description We are seeking a highly motivated and talented Scientist to join our Translational Retinal Research Laboratory @ Institute of Molecular and Cell Biology (IMCB). The successful candidate will lead innovative research programmes focused on understanding retinal disease mechanisms and developing next­generation therapies for Age-related Macular Degeneration {AMD) and other retinal diseases. The Scientist will integrate advanced stem cell biology, retinal disease modelling, and multi-omics approaches to identify disease mechanisms, therapeutic targets, and biomarkers that can accelerate translational development and clinical impact. Responsibilities • Design, execute, and optimize experiments involving stem cell-derived retinal cell types, including retinal pigment epithelium (RPE) and related ocular cell populations. • Develop and apply advanced in-vitro retinal disease models to investigate disease mechanisms and therapeutic interventions. • Generate, analyse, and interpret complex biological datasets to identify disease-associated pathways, biomarkers, and therapeutic targets. • Collaborate closely with bioinformaticians, clinicians, and multidisciplinary research teams to integrate molecular, cellular, imaging, and functional datasets. • Contribute to the development and evaluation of novel biologic therapies for retinal diseases. • Mentor Research Officers and interns in experimental design, laboratory techniques, and data analysis. • Present research findings at internal meetings, scientific conferences, and external collaborations. • Prepare manuscripts for publication in peer-reviewed journals and contribute to grant applications, progress reports, and intellectual property disclosures. • Maintain accurate scientific records and ensure compliance with institutional, biosafety, and regulatory requirements. Job Requirements • PhD in Stem Cell Biology, Neuroscience, Ophthalmology, Cell Biology, Molecular Biology, Biomedical Sciences, Bioengineering, or a related discipline. • Strong publication record demonstrating independent scientific contributions. • Experience in one or more of the following areas: • Retinal biology • Stem cell biology • Regenerative medicine • Hands-on experience with advanced molecular and cellular techniques including cell culture, gene expression analysis, imaging, immunohistochemistry, and functional assays. • Experience with single-cell sequencing, bioinformatics, or other omics-based technologies is highly desirable but not necessary. • Familiarity with data analysis using R, Python, or related computational tools is advantageous. • Demonstrated ability to independently design experiments, troubleshoot technical challenges, and drive projects forward. • Excellent scientific writing, presentation, and communication skills. • Strong collaborative mindset with the ability to work effectively in multidisciplinary teams.